This is what the cat scan showed. I figured out that I have had some obstruction ever since I was pregnant with Sibley. They told me during my ultrasound way back then that she was blocking my right kidney. That explains why I have had frequent UTIs and intermittent blood in my urine ever since then. I think I must have gotten a kidney stone pretty soon before Christmas, which aggravated my situation and things have gone downhill ever since then. See there - mystery solved!
OVERVIEW
The ureter is a long thin tubular structure 10-12 inches long which carries urine produced in the kidney to the bladder. The urine is transported by a process called peristalsis. The ureter actively propels urine from the kidney down into the bladder.
Ureteropelvic junction obstruction is a condition where blockage occurs at the junction where the ureter attaches to the kidney. This results in decreased flow of urine down the ureter and an increase of fluid pressure inside the kidney. Increased pressure inside the kidney can over time cause deterioration of kidney function. The obstruction can be either congenital (the patient is born with it) or develop over time secondary to trauma or change in body shape with age. The blockage can be due to scar tissue, kinking, a blood vessel or rarely tumor.
SIGNS AND SYMPTOMS
Ureteral obstruction can cause flank pain on the effected side. The pain may be intermittent and some patients notice increased pain when drinking alcohol, coffee or increased fluids. The pain can sometimes be in the front of the abdomen and can radiate down to the groin. In some instances, the condition is detected accidently on x-rays or ultrasound during evaluation for unrelated problems. When infection occurs in association with obstruction, patients can become quite ill and have high fevers. This condition may require hospitalization, emergency drainage of the urine and treatment with intravenous antibiotics.
TREATMENTS
The traditional treatment for ureteropelvic junction obstruction has been open surgery to cut out the area of scarring and re-connect the ureter to the kidney. Over the past several years, newer less invasive treatment options have been developed.
Endopyelotomy is a procedure through which a telescope or balloon with an electric wire on it is passed to the level of the kidney. The scar tissue is then cut open from the inside. These procedures can be done in a short period of time as an outpatient with minimal anesthetic and with a much shorter recuperation than with open surgery. Patients will have to keep a temporary internal tube (stent) for four to six weeks. The radiographic success rate with these procedures are 15%-20% lower than what is obtained with open surgery. Moreover, 40% of patients may have significant persistent pain following procedure.
Laparoscopic Pyeloplasty was developed in order to give the same high success rate obtained with open pyeloplasty while decreasing the morbidity. The internal procedure is performed in the same manner as the open surgery without the need for a large incision. Postoperative pain is less, recuperation is significantly quicker and scarring is minimal when compared with open surgery. The procedure requires a general anesthetic and hospitalization (usually 2 nights). An internal stent is also needed for four weeks. Success with this procedure is the same as open surgery (>95%).
Click here for more details...© Copyright 2008 All Rights Reserved
Disclaimer Email:
mailto:webmaster@urology.jhu.edu600 North Wolfe Street, Baltimore, Maryland 21287
Hydronephrosis is distention (dilation) of the kidney with urine, caused by backward pressure on the kidney when the flow of urine is obstructed.
Kidney stones are common causes of urinary tract obstruction.
When hydronephrosis occurs quickly, people may have excruciating pain, most often in the flank (the area between the ribs and the hips).
When hydronephrosis occurs more gradually, people may have no symptoms or experience attacks of dull, aching discomfort in the flank.
Doctors initially use bladder catheterization (or ultrasonography) to detect hydronephrosis, and they may use ultrasonography or another imaging test to determine the site of the blockage.
Treatment depends on the cause of the obstruction.
Hydronephrosis: A Distended Kidney
In hydronephrosis, the kidney is distended because the flow of urine is obstructed and urine backs up in the kidney's small tubes and central collecting area (renal pelvis).
Normally, urine flows out of the kidneys at extremely low pressure. If the flow of urine is obstructed, urine backs up behind the point of blockage, eventually reaching the small tubes of the kidney and its collecting area (renal pelvis), distending the kidney and increasing the pressure on its internal structures. The elevated pressure from obstruction may ultimately damage the kidney and can result in loss of its function. When the flow of urine is obstructed, urinary tract infections are fairly common and stones are more likely to form. If both kidneys are obstructed, kidney failure may result.
Long-standing distention of the renal pelvis and ureter can also inhibit the rhythmic muscular contractions that normally move urine down the ureter from the kidney to the bladder (peristalsis). Scar tissue may then replace the normal muscular tissue in the walls of the ureter, resulting in permanent damage.
Causes
Hydronephrosis commonly results from an obstruction located at the junction of the ureter and renal pelvis (ureteropelvic junction). Causes of this type of obstruction include the following:
Structural abnormalities—for example, a birth defect in which the insertion of the ureter into the renal pelvis is too high or there is inadequate development of the ureteral muscles (congenital ureteropelvic junction obstruction)
Kinking at the ureteropelvic junction resulting from a kidney shifting downward (ptosis of the kidney)
Stones (calculi) or a blood clot in the renal pelvis
Compression of the ureter by bands of fibrous tissue, an abnormally located artery or vein, or a tumor
Hydronephrosis can also result from an obstruction below the ureteropelvic junction or from backflow (reflux) of urine from the bladder. Causes of this type of obstruction include the following:
Stones in the ureter
Blood clot in the ureter
Tumors in or near the ureter
Narrowing of the ureter resulting from a birth defect, an injury, an infection, radiation therapy, or surgery
Disorders of the muscles or nerves in the ureter or bladder
Formation of fibrous tissue in or around the ureter resulting from surgery, radiation therapy, or drugs (especially
methysergideSome Trade Names SANSERT)
Bulging of the lower end of the ureter into the bladder (ureterocele)
Cancers of the bladder, cervix, uterus, prostate, or other pelvic organs
Obstruction that prevents urine flow from the bladder to the urethra, resulting from prostate enlargement (most often caused by a condition called benign prostatic hyperplasia—see
Prostate Disorders: Benign Prostatic Hyperplasia (BPH)), or rectal impaction with feces
Abnormal contractions of the bladder resulting from a birth defect or a spinal cord or nerve injury
Hydronephrosis of both kidneys can occur during pregnancy as the enlarging uterus compresses the ureters. Hormonal changes during pregnancy may aggravate the problem by reducing the muscular contractions that normally move urine down the ureters. This condition, commonly called hydronephrosis of pregnancy, usually ends when the pregnancy ends, although the renal pelvis and ureters may remain somewhat distended afterward.
Symptoms
Symptoms depend on the cause, location, and duration of the obstruction. When the obstruction begins quickly (acute hydronephrosis), it usually produces renal colic—an excruciating, intermittent pain in the flank (the area between the ribs and hip) on the affected side. Obstruction on one side does not reduce urine flow. Obstruction can stop or reduce urine flow if blockage affects the ureters from both kidneys or if it affects the urethra. Obstruction of the urethra or bladder outlet may produce pain, pressure, and distention of the bladder.
People who have slowly progressive (chronic) hydronephrosis may have no symptoms, or they may have attacks of dull, aching discomfort in the flank on the affected side. Sometimes a kidney stone temporarily blocks the ureter and produces painful hydronephrosis that occurs intermittently.
Hydronephrosis may cause vague intestinal symptoms, such as nausea, vomiting, and abdominal pain. These symptoms sometimes occur in children when hydronephrosis results from a birth defect in which the junction of the ureter and renal pelvis is too narrow (ureteropelvic junction obstruction).
People who have urinary tract infections may have pus in the urine, fever, and discomfort in the area of the bladder or kidneys.
Diagnosis
Early diagnosis is important, because most cases of obstruction can be corrected and because a delay in treatment can lead to irreversible kidney damage. Doctors may suspect hydronephrosis because of a person's symptoms and sometimes because of findings discovered during a physical examination. A distended kidney can occasionally be felt in the flank, particularly if the kidney is greatly enlarged in an infant or a child or a thin adult. A distended bladder can sometimes be felt in the lower part of the abdomen just above the pubic bone.
Doctors depend on testing to make the diagnosis. Bladder catheterization (insertion of a hollow, flexible tube through the urethra) is often the first diagnostic test done in people with renal colic, pelvic pressure, or distention. If the catheter drains a large amount of urine from the bladder, then either the bladder outlet or the urethra is obstructed. Many doctors do ultrasonography to determine whether the bladder is filled with a large amount of urine before doing bladder catheterization.
If the presence or site of obstruction is in doubt, various imaging tests can be done to identify evidence of obstruction such as hydronephrosis or a site of blockage. For example, ultrasonography is a very useful test in most people (particularly children and pregnant women) because it is fairly accurate and does not expose the person to any radiation. Computed tomography (CT) scanning is an alternative. It is rapid and highly accurate, particularly at identifying stones. Other imaging tests, such as intravenous urography, may be performed to identify the site of obstruction, if it is not visible with ultrasonography or CT.
An endoscope (a rigid or flexible telescope) is sometimes used to look at possible sites of obstruction as closely as possible. An endoscope can be used to examine the urinary tract.
Blood and urine tests are done. Blood test results are usually normal, but tests may reveal high levels of urea nitrogen (sometimes called BUN), creatinine, or both, if obstruction affects both kidneys. Results from an analysis of urine (urinalysis) are usually normal but white blood cells and red blood cells may be present when a stone or a cancer is the cause of obstruction, or when the obstruction is complicated by an infection.
Prognosis
Permanent kidney damage is unlikely to result unless both kidneys are obstructed for at least a few weeks. The prognosis is less certain for chronic hydronephrosis.
Treatment
Treatment usually aims to relieve the cause of obstruction. For example, if the urethra is obstructed because of an enlarged or cancerous prostate, treatment can include drugs, such as hormone therapy for prostate cancer (see
Prostate Disorders: Cancer), surgery, or enlargement of the urethra with dilators. Other treatments, such as lithotripsy or endoscopic surgery, may be needed for stones that block the flow of urine. If the cause of obstruction cannot be rapidly corrected, particularly if there is infection, kidney failure, or severe pain, the urinary tract is drained. In acute hydronephrosis, urine that has accumulated above the obstruction can be drained with a soft tube inserted through the skin into the kidney (nephrostomy tube) or by insertion of a soft plastic tube that connects the bladder with the kidney (ureteral stent). Complications of nephrostomy tubes or ureteral stents can include displacement of the tube, infection, and discomfort.
Urgent relief of chronic hydronephrosis is usually not required. Complications of hydronephrosis, such as urinary tract infections and kidney failure, if present, are treated promptly.
Last full review/revision August 2007 by Glenn M. Preminger, MD
Back to TopPrevious:
IntroductionNext:
Stones in the Urinary Tract